[e-drug] Mefloquin for malaria prophylaxis (cont)

["Suleman Khatija\\Natalnbi" <natalnbi@nbi-kzn.org.za>]

E-drug: Mefloquin for malaria prophylaxis (cont)
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Hi

In light of this what would the recommendation for children under 
13's be for prophylaxis if they cannot tolerate mefloquine; 
considering that they cannot take doxycycline due to deposition in 
bones and teeth?

___________________________
Khatija Suleman
Information Pharmacist
Natal Bioproducts Institute
Private Bag X9043
Pinetown
3600

Tel: + 27 31 719 6789
Fax: + 27 31 708 5614
E-mail: natalnbi@nbi-kzn.org.za
Web site: www.nbi-kzn.org.za
[Doxycycline is not recommended for children 8 years of age or 
younger. Mefloquine is not approved for use in children in Australia 
but has been used in other countries: (using 250 mg tablet)15-19kg - 
1/4 tablet; 20-30kg 1/2 tablet; 31-40 kg 3/4 tablet orally, weekly, 1 
week prior to 4 weeks after leaving malarious area.  Chloroquin and 
proguanil have been widely used in children and pregnant women. 
Other alternative is good physical protection with clothing, bednets, 
repellant.  BS]
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